The blue-chip index rose 0.7% with medical products maker Smith+Nephew jumping 4.6% to the top of the index after it reinstated its 2021 outlook following revenue growth in first quarter.
The index was also supported by Unilever, which rose 3.5% after it beat quarterly sales forecasts, helped by a pick up in home cooking during coronavirus lockdowns and a strong economic recovery in China.
The domestically focused midcap FTSE 250 index advanced 0.2%.
WH Smith slipped 4.6% after it warned of the possible risk of breaching its covenant tests in 2022 and launched a potential 325 million-pound ($450 million) bonds offering as the retailer navigates the COVID-19 pandemic.
(Reporting by Devik Jain in Bengaluru; Editing by Shounak Dasgupta)